endometrial receptivity

What is the Endometrial
Receptivity Test (ERA)?

The endometrial receptivity test is a test that determines the ideal moment to perform an embryo transfer, also known as the implantation window. This timing can differ depending on the patient. We know that 3 out of 10 patients have a displaced implantation window. The endometrium is the mucous membrane that covers the inner part of the uterus. It changes during the menstrual cycle and prepares itself for embryo implantation. It will only be “receptive” when it has the right thickness and the necessary conditions to allow a dialogue between the embryo and the endometrium.

The endometrium is only receptive for a short period of time, from 12 to 48 hours. But this is not always the case: it is crucial to know the details of each patient’s implantation window to increase the chances of embryo implantation.

endometrial receotivity
Preimplantation Genetic Testing

How is it for?

The endometrial receptivity test is recommended in IVF, Egg Donation, Embryo donation and ROPA method treatments since the transfer should be performed at the moment of maximum receptivity. This test is particularly important in the following cases:

  • History of implantation failure in previous treatments after transfer of good quality embryos.
  • Unexplained infertility.
  • Treatments in which a preimplantation genetic testing (PGT) is performed.

For each patient, Vida Fertility Institute specialists will do everything to determine the causes of infertility and find the most appropriate solutions for their case. Sometimes, the endometrial receptivity test is combined with the endometrial immunology test to complete the study and increase the chances of the embryo implantation.

What’s the Endometrial Receptivity procedure?

The endometrial receptivity test is a very simple test that consists of taking a small sample of endometrial tissue after completing an endometrial preparation cycle. The purpose of this test is to reproduce the exact conditions of an embryo transfer, to check if the endometrium meets the right conditions for future embryo implantation and to determine the exact moment to plan the embryo transfer.

Endometrial preparation is a simple treatment, involving the administration of estrogen and progesterone, orally, vaginally or by patch. At the time of what would be a “normal” implantation window, we will perform an endometrial biopsy. Depending on the results of the receptivity study of this sample, we will plan the precise time of the embryo transfer.

endometrial receptivity