Genetic Compatibility Test

What is the Genetic Compatibility Test (GCT)?

The Genetic Compatibility Test (GCT) is used to detect any genetic mutations in the couple or in the gamete donors, in order to prevent the transmission of recessive hereditary diseases to future children.

Recessive diseases refer to all genetic alterations that occur in both copies of the same gene (one copy transmitted by the father and the other by the mother). Thanks to the genetic compatibility test, we can find out whether both parents are carriers of the same alteration.

for who is
Who is it for?

The Genetic Compatibility Test is intended for all patients who wish to know this information before seeking pregnancy or undergoing fertility treatment. It is estimated that everyone carries about 15 genetic alterations and, in most cases, this does not cause any disease. Since only one copy of the gene is involved and the other copy of the gene is normal, it is sufficient to prevent the disease. Those who carry mutations are healthy and asymptomatic and there is no medical indications for carrying out this test.

However, our specialists usually advise the Genetic Compatibility Test in the case of gamete donation (semen or oocytes). Indeed, the results obtained in the carrier panels will allow a better selection of donors, avoiding coincidences in genetic alterations.

This test is a completely personal decision when there is no medical indication, and our experts will be available to offer you all the information you need to make your choice.

What is the procedure for the Genetic Compatibility Test?

The process for carrying out this test is fairly straightforward, involving taking a blood or saliva sample from patients and/or gamete donors. Once we have received the test results, we can compare the results of the two parents by genetic matching, and detect whether there is a risk of having a child suffering from one of the diseases studied by the test. If there is an incompatibility in the couple, we will then recommend that a Preimplantation Genetic Testing be carried out on the embryos obtained. In the case of donor treatment, if there is an incompatibility, the medical team will select another compatible donor.

what is the process