Genetic Compatibility Test: What is it for?

Genetic Compatibility Test: What is it for?

What is the Genetic
Compatibility Test (GCT)?

The Genetic Compatibility Test (GCT) allows the detection of possible genetic mutations, either in the couple or in the gamete donors, in order to avoid the transmission of recessive hereditary diseases to their future children.

Recessive diseases are genetic alterations that occur when two copies of the same gene are damaged (one copy transmitted by the father and the other by the mother). Thanks to the genetic compatibility test we will be able to know if both parents are carriers of the same alteration.

For whom is it?

The Genetic Compatibility Test is intended for all patients who wish to know this information before seeking pregnancy or initiating fertility treatment. It is estimated that all people carry about 15 genetic alterations and, in most cases, this does not cause any disease, since only one copy of the gene is involved and the other copy of the gene is normal and therefore sufficient to prevent the disease. Those who carry mutations are healthy and asymptomatic and there is no major reason why this test should be indicated.

However, our specialists usually advise the Genetic Compatibility Test in case of resorting to gamete donation (semen or oocytes), since the results obtained in the carrier panels will allow a better selection of donors, avoiding coincidences in genetic alterations.

The realization of this test is a totally personal decision when there is no medical indication, and our experts will be available to offer you all the necessary information to accompany you in your decision.

What is the Genetic Compatibility
Test process like?

The process of performing this test is quite simple since it will be done by means of a blood or saliva sample in patients and/or gamete donors. After receiving the results of the carrier panel, we will be able to compare the results of both with the genetic matching, and detect if there is a risk of having a child affected by any of the diseases studied by this test. If there is an incompatibility in a couple, we would indicate the performance of Preimplantational Diagnosis in the embryos obtained. In case of treatment with donors, if there is any genetic incompatibility, the medical team will select another compatible donor.