Fertile Chip: Optimizing Success in Assisted Reproduction Treatments

Fertile Chip

The assisted reproduction technique known as Fertile Chip has been designed to choose healthy and mobile sperm for use in fertility treatments.

In a discussion with Beatriz Lozano, a specialist embryologist at Vida Fertility, we explore the benefits of Fertile Chip, who it’s recommended for, and potential risks.

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The Fertile Chip is an innovative device streamlining the selection of sperm with enhanced mobility and reduced DNA fragmentation. Acting as a filter, it precisely separates high-quality sperm for use in fertility procedures.

Designed with interconnected input and output chambers linked by a tiny microfluidic channel, this advanced system optimizes the process. The sperm sample is introduced into the input chamber, and after a specific period, the sperm that have reached the collection chamber are selected.

The Fertile Chip stands out for its modern approach. Its effective application not only improves conception chances but also significantly reduces the risk of spontaneous abortion.

Benefits of Fertile Chip

The Fertile Chip is a state-of-the-art microfluidic device specifically designed for selecting high-quality sperm in assisted reproduction treatments such as in vitro fertilization (IVF) and intrauterine insemination (IUI).

  • No need for semen sample processing
  • Sample does not require processing
  • Simple and fast
  • Monitoring through a microscope
  • Embryo culture remains unaffected

In summary, this method poses no additional risks, reduces oxidative stress in the sample, allows for improved selection of high-quality sperm, directly impacting the success of assisted reproduction treatments by enhancing embryo quality and providing hope and opportunities for those seeking to start a family.

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Fertile Chip is advised when there is high DNA fragmentation in the sperm sample, which can hinder natural conception.

Additionally, this technique is recommended in the following cases:

  • Women who experienced slow embryonic development in previous cycles.
  • Those who faced implantation failures in previous IVF cycles. 
  • Women experiencing recurrent miscarriages.

Fertile Chip is intended for use with fresh semen samples with a minimal sperm concentration. Due to its channel and fluid flow design, a certain percentage of motile sperm is necessary to ensure the technique’s proper functioning. Therefore, it is not recommended for cryopreserved samples or those that do not meet the minimum concentration and motility requirements.

User Questions about Fertile Chip

How long does it take to collect sperm with Fertile Chip?

When the sperm sample is introduced into the Fertile Chip’s input chamber, it is left to incubate at room temperature (37ºC) for approximately 30 minutes.

During this time, sperm move to the collection chamber and, once this period is over, they are collected for use in the IVF laboratory.

Is Fertile Chip better than MACS?

Fertile Chip is better for men with sperm DNA fragmentation, especially double-strand fragmentation. On the other hand, MACS technique helps reduce the number of sperm with fragmentation.

Does it have any limitations, or can all patients undergo the procedure?

Fertile Chip is not recommended for patients with severe male factor infertility, as it will be difficult to recover sufficient sperm. It is also not recommended for pre-frozen semen samples.

These innovative tools, developed by Vida Fertility, open new perspectives and opportunities for those seeking to build their family through assisted reproduction treatments. In the pursuit of excellence and hope, Fertile Chip and SpermSlow as essential allies on this journey to motherhood.

Contact us for more information!

Predicting egg quality

Vida Fertility implements VIOLET™, an artificial intelligence system trained on a large dataset of oocyte images, to predict oocyte quality and reproductive potential in an individualized, non-invasive manner before vitrification.

congelar óvulos violet
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Where can I find Vida Fertility centres in Spain?


📍 C/ Palermo 15, Hortaleza, 28043 Madrid
📞 Phone number: +34 919 29 83 23
🕒 Opening hours: Monday to Friday from 8am to 7pm


📍 Av. Óscar Esplá 1, Bajo, 03008 Alicante
📞 Phone number: +34 919 29 83 23
🕒 Opening hours: Monday to Friday from 8am to 7pm

ℹ️ The information published on Vida Fertility is reviewed by our fertility specialists and medical team, following up-to-date scientific criteria and evidence-based medicine. Our team is a member at scientific societies such as SEF, ESHRE and SEGO.